Cancer
I noticed a lot of posts on some boards asking why the President Roslin has to have cancer.
I think this is a kind of clever plot device that may be used if the series is picked up and Mary McDonnell doesn't want to continue (opting for movies instead). When she wants out, her character dies much like Jane Seymour's character in TOS. Plus it would bring an interesting plot element and pathos with it.
I think they have sketched this out pretty well. I'm excited to see where it takes us.
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